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John Wayne Casserole

Hey there! So, you know those recipes that just bring back memories of crowded family dinners? John Wayne Casserole is one of those for me. Picture this: a rowdy Sunday afternoon, the kids are making a racket, and I’m trying to whip up something that everyone will actually eat. This casserole—named after the Duke himself, no less!—is a lifesaver. It’s got all the good stuff: beef, cheese, and a bit of a spicy kick. My kids used to call it ‘Cowboy Pie,’ and honestly, I think that’s a better name.

Why You’ll Love This

I whip this up when we’re all craving something hearty. My family goes bananas for it because it’s like a fiesta in a dish (minus the sombreros). It’s not one of those fancy soufflés that collapses when you look at it wrong; it’s forgiving and versatile. I mean, I’ve burnt the edges a couple of times, and they still gobbled it up. It’s a go-to when you want to impress without too much stress.

Ingredients You’ll Need

  • 1 lb ground beef (sometimes I swap for turkey when feeling fancy)
  • 1 packet taco seasoning (store-bought is fine, but if you’re up for it, homemade is even better!)
  • 4 oz canned diced green chiles (I once used fresh peppers—wasn’t quite the same)
  • 1 can (14 oz) diced tomatoes, drained
  • 1/2 cup sour cream (Greek yogurt works too, but don’t tell my husband)
  • 1/2 cup mayonnaise (I know, but trust me!)
  • 8 oz cheddar cheese, shredded (or a cheese blend if you’re feeling adventurous)
  • 1 cup biscuit mix (I just use Bisquick, though my grandma swore by homemade)
  • 1 cup milk
  • 2 eggs

Let’s Get Cooking

  1. Preheat your oven to 350°F (175°C). This is where I usually take a sip of coffee and mentally prep for the chaos.
  2. In a skillet, brown the ground beef over medium heat. Drain any excess fat (but save a bit for flavor, because yum!). Stir in the taco seasoning, green chiles, and tomatoes. Let it simmer for about 5 minutes. It should smell amazing right about now.
  3. In a medium bowl, mix the sour cream, mayonnaise, and half of the cheese. This is where I sneak a taste—quality control!
  4. In a separate bowl, combine the biscuit mix, milk, and eggs. Pour this into a greased baking dish. It may look a bit runny, but don’t worry; it’s supposed to.
  5. Layer the beef mixture over the batter, then slather the sour cream mixture on top. Sprinkle the remaining cheese over everything.
  6. Bake for about 30-35 minutes. The top should be golden and bubbly. If you’re anything like me, this is the hardest part—waiting!

Notes from My Kitchen

One time, I tried using low-fat cheese to be healthy. Let’s just say it didn’t quite melt the way I wanted. Stick to the real stuff if you can.

Variations I’ve Tried

I swapped the beef for chicken once, and the family loved it. But the time I added olives? Nope, learned my lesson there—it was a no-go.

What If You Don’t Have…

No biscuit mix? No worries! Just use a cup of flour with a pinch of baking powder and salt. Easy peasy!

John Wayne Casserole

Storing This (If There’s Any Left)

You can store leftovers in the fridge for up to 3 days. Although, honestly, it never lasts more than a day in my house!

How We Serve It Up

We usually have it with a simple green salad or some roasted veggies. My brother insists on a dollop of salsa on the side.

Top Tips (Learned the Hard Way)

Don’t rush the beef browning. I once tried speeding things up and ended up with a soggy mess. Patience, my friend!

FAQs I’ve Heard

Can I make this ahead of time? Absolutely! Just prep it and pop it in the fridge. Bake it when you’re ready.

Can I freeze leftovers? Yep, just wrap ’em up tight. They’ll keep for a couple of months. But try to remember they’re in there!

★★★★★ 4.80 from 120 ratings

John Wayne Casserole

yield: 6 servings
prep: 20 mins
cook: 40 mins
total: 50 mins
A hearty and flavorful casserole featuring layers of ground beef, cheese, and vegetables, perfect for a satisfying dinner.
John Wayne Casserole

Ingredients

  • 1 pound ground beef
  • 1 packet taco seasoning
  • 1/2 cup sour cream
  • 1/2 cup mayonnaise
  • 1 cup shredded cheddar cheese
  • 1 medium onion, chopped
  • 1 bell pepper, chopped
  • 2 cups biscuit mix
  • 1 cup milk

Instructions

  1. 1
    Preheat oven to 350°F (175°C).
  2. 2
    In a skillet, cook ground beef with taco seasoning until browned. Drain excess fat.
  3. 3
    In a bowl, mix sour cream, mayonnaise, and half of the cheese. Set aside.
  4. 4
    In a separate bowl, combine biscuit mix and milk to form a dough. Press into the bottom of a greased baking dish.
  5. 5
    Layer cooked beef, onion, and bell pepper over the dough. Spread the sour cream mixture on top and sprinkle with remaining cheese.
  6. 6
    Bake for 40 minutes or until the top is golden and bubbly. Let cool slightly before serving.
CLICK FOR NUTRITION INFO

Approximate Information for One Serving

Serving Size: 1 serving
Calories: 450 caloriescal
Protein: 20 gramsg
Fat: 25 gramsg
Saturated Fat: 0g
Trans Fat: 0g
Cholesterol: 0mg
Sodium: 0mg
Potassium: 0mg
Total Carbs: 30 gramsg
Fiber: 0g
Sugar: 0g
Net Carbs: 0g
Vitamin A: 0
Vitamin C: 0mg
Calcium: 0mg
Iron: 0mg

Nutrition Disclaimers

Number of total servings shown is approximate. Actual number of servings will depend on your preferred portion sizes.

Nutritional values shown are general guidelines and reflect information for 1 serving using the ingredients listed, not including any optional ingredients. Actual macros may vary slightly depending on specific brands and types of ingredients used.

To determine the weight of one serving, prepare the recipe as instructed. Weigh the finished recipe, then divide the weight of the finished recipe (not including the weight of the container the food is in) by the desired number of servings. Result will be the weight of one serving.

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